Metabotropic Glutamate Receptor 5 anticorps (AA 431-530) (HRP)

N° du produit ABIN6944080

L’anticorps Lapin Polyclonal anti-Metabotropic Glutamate Receptor 5 a été validé pour WB et ELISA. Il convient pour détecter Metabotropic Glutamate Receptor 5 dans des échantillons de Rat et Souris.

Aperçu rapide pour Metabotropic Glutamate Receptor 5 anticorps (AA 431-530) (HRP) (ABIN6944080)

Antigène: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 5 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-Metabotropic Glutamate Receptor 5 anticorps (HRP)

Épitope: AA 431-530

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Sheep,Horse,Chicken,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MGLUR5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Metabotropic Glutamate Receptor 5

Antigène: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Autre désignation: MGLUR5

Sujet:

Synonyms: MGLUR5B, Glutamate receptor metabotropic 5, GPRC1E, GRM 5, GRM5, Metabotropic glutamate receptor 5, mGlu5, mGluR5, mGluR5a, mGluR5b, Metabotropic glutamate receptor 5 variant F, Metabotropic Glutamate Receptor 5b, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, PPP1R86, GRM5_HUMAN,

Background: Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.

ID gène: 2915

UniProt: P41594

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity