POR anticorps
Aperçu rapide pour POR anticorps (ABIN6944641)
Antigène
Voir toutes POR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Réactivité croisée
- Humain, Souris, Rat
-
Purification
- Purified by Protein A.
-
Immunogène
- Recombinant protein within human Cytochrome P450 Reductase aa 1-150
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
Date de péremption
- 12 months
-
-
- POR (P450 (Cytochrome) Oxidoreductase (POR))
-
Autre désignation
- POR
-
Sujet
-
Synonyms: NADPH cytochrome P450 reductase, CPR, P450R, POR, CYPOR, Cytochrome p450 Reductase
Background: Cytochrome P450 Oxidoreductase is an endoplasmic reticulum membrane oxidoreductase with a FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. It can also provide electron transfer to heme oxygenase and cytochrome B5.
-
ID gène
- 5447
-
UniProt
- P16435
-
Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
Antigène
-