PTPN12 anticorps (AA 1-100)

N° du produit ABIN6944721

Cet anticorps Lapin Polyclonal détecte spécifiquement PTPN12 dans WB, ELISA, IF (p), IHC (p), IF (cc), ICC et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour PTPN12 anticorps (AA 1-100) (ABIN6944721)

Antigène: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PTPN12 anticorps

Épitope: AA 1-100

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PTPN12

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PTPN12

Antigène: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Autre désignation: PTPN12

Sujet:

Synonyms: Protein tyrosine phosphatase G1, Protein tyrosine phosphatase non receptor type 12, Protein-tyrosine phosphatase G1, PTN12_HUMAN, PTP PEST, PTP-PEST, PTPG1, Ptpn12, Tyrosine protein phosphatase non receptor type 12, Tyrosine-protein phosphatase non-receptor type 12.

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

ID gène: 5782

UniProt: Q05209