Reelin anticorps
Aperçu rapide pour Reelin anticorps (ABIN6944773)
Antigène
Voir toutes Reelin (RELN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein A.
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Immunogène
- Human Reelin aa 241-340
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 12 months
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- Reelin (RELN)
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Autre désignation
- Reelin
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Sujet
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Synonyms: Reelin, RELN
Background: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
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ID gène
- 5649
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UniProt
- P78509
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Pathways
- Synaptic Membrane
Antigène
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