Sonic Hedgehog anticorps (AA 250-350)

N° du produit ABIN6944987

Cet anticorps anti-Sonic Hedgehog Monoclonal Lapin (Clone 4C10) (ABIN6944987) détecte spécifiquement Sonic Hedgehog dans WB, IHC, FACS, IHC (p) et IF (cc). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Sonic Hedgehog anticorps (AA 250-350) (ABIN6944987)

Antigène: Sonic Hedgehog (SHH)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Sonic Hedgehog est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 4C10

Détail du produit anti-Sonic Hedgehog anticorps

Épitope: AA 250-350

Fonction: Sonic Hedgehog Protein (C-Product) (4C10) Monoclonal Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Human Sonic Hedgehog between 250-350 amino acids

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:200-400), IHC-P(1:100-500), IF(ICC)(1:50-200), IHC()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Sonic Hedgehog

Antigène: Sonic Hedgehog (SHH)

Autre désignation: Sonic Hedgehog Protein (C-Product)

Sujet:

Synonyms: Sonic hedgehog protein, HHG-1, SHH

Background: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).

ID gène: 6469

UniProt: Q15465

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development