PRNP anticorps

N° du produit ABIN6944654

Cet anticorps anti-PRNP est un anticorps Lapin Monoclonal détectant PRNP dans WB, IHC, IF (cc) et FACS. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour PRNP anticorps (ABIN6944654)

Antigène: PRNP (Prion Protein (PRNP))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PRNP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

Clone: 33A5

Détail du produit anti-PRNP anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: C terminal human Prion protein

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200), IHC()

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PRNP

Antigène: PRNP (Prion Protein (PRNP))

Autre désignation: Prion Protein (PrP)

Sujet:

Synonyms: Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP

Background: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

ID gène: 5621

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation