TGFBR1 anticorps

N° du produit ABIN6950907

Cet anticorps anti-TGFBR1 Monoclonal Souris (ABIN6950907) détecte spécifiquement TGFBR1 dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour TGFBR1 anticorps (ABIN6950907)

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFBR1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-TGFBR1 anticorps

Fonction: TGF β Receptor I mouse mAb

Specificité: The antibody can specifically recognize human TGF β Receptor I protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogène: A synthetic peptide corresponding to the amino acid region 34 - 100 of the human TGF beta Receptor I protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur TGFBR1

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Autre désignation: TGF beta Receptor I

Sujet:

Synonyms: AAT5, ALK5, ESS1, LDS1, MSSE, SKR4, TBRI, ALK-5, LDS1A, LDS2A, TBR-i, TGFR-1, ACVRLK4, tbetaR-I, TGF beta Receptor I (TGFBR1)

Background: Members of the transforming growth factor β (TGF-β) superfamily are key regulators of cell proliferation, differentiation, development, morphogenesis, and disease pathogenesis. TGF-β signals through three cell surface receptors: type I (RI), type II (RII), and type III (RIII). Type I and type II receptors are serine/threonine kinases that form heteromeric complexes. Upon ligand binding, type II receptors form a stable complex with type I receptors, leading to phosphorylation and activation of the type I receptor kinase.

Gene Name: TGFBR1 ALK5 SKR4

Protein Name: TGF β Receptor I

ID gène: 7046

UniProt: P36897

Pathways: Growth Factor Binding