BRD4 anticorps (N-Term)

N° du produit ABIN6952374

L’anticorps Lapin Polyclonal anti-BRD4 a été validé pour WB, ELISA, ChIP et ChIP-seq. Il convient pour détecter BRD4 dans des échantillons de Humain.

Aperçu rapide pour BRD4 anticorps (N-Term) (ABIN6952374)

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRD4 est non-conjugé

Application: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-BRD4 anticorps

Épitope: N-Term

Specificité: Polyclonal antibody raised in rabbit against human BRD4 (Bromodomain Containing 4), using two KLH-conjugated synthetic peptides from the N-terminal and central part of the protein, respectively.

Purification: Peptide affinity purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP 2 μg:ChIP
ELISA 1:10,000
WB 1:1,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.6 μg/μL

Buffer: PBS, 0.05 % azide, 0.05 % ProClin300

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur BRD4

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Autre désignation: BRD4

Sujet: BRD4 (UniProt/Swiss-Prot entry O60885) is a chromatin reader protein that binds acetylated histones. It remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for gene transcription by preserving an acetylated chromatin status. As such, it plays a key role in the transmission of epigenetic memory across cell divisions. BRD4 promotes phosphorylation of Ser-2 of the C-terminal domain (CTD) of RNA polymerase II and plays a key role in regulating the transcription of signal-inducible genes. It has been implicated in a translocation of chromosome 19 which causes an upper respiratory tract carcinoma.

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome