HDAC3 anticorps (C-Term)

N° du produit ABIN6952382

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC3 dans ELISA, ChIP et ChIP-seq. Il présente une réactivité envers Humain.

Aperçu rapide pour HDAC3 anticorps (C-Term) (ABIN6952382)

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC3 est non-conjugé

Application: ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-HDAC3 anticorps

Épitope: C-Term

Specificité: Polyclonal antibody raised in rabbit against human HDAC3 (Histone deacetylase 3), using two KLH-conjugated synthetic peptides from the central and the C-terminal part of the protein, respectively.

Purification: Peptide affinity purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP/ChIP-seq 2 μg:ChIP
ELISA 1:10,000
WB not recommended

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.7 μg/μL

Buffer: PBS, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur HDAC3

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Autre désignation: HDAC3

Sujet: HDAC3 (UniProt/Swiss-Prot entry O15379) catalyses the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) and on some other non-histone substrates. Acetylation and deacetylation of these highly conserved lysine residues is important for the control of gene expression. When tethered to a promoter, HDAC3 represses transcription and therefore plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC3 probably participates in the regulation of transcription through its binding to the YY1 transcription factor, increasing YY1 repression. HDAC3 also downregulates p53 and is considered a potential tumor suppressor gene.

UniProt: O15379

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development