Retinoic Acid Receptor alpha anticorps (C-Term)

N° du produit ABIN6952387

Cet anticorps anti-Retinoic Acid Receptor alpha Polyclonal Lapin (ABIN6952387) détecte spécifiquement Retinoic Acid Receptor alpha dans WB, ELISA, ChIP et ChIP-seq. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Retinoic Acid Receptor alpha anticorps (C-Term) (ABIN6952387)

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoic Acid Receptor alpha est non-conjugé

Application: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-Retinoic Acid Receptor alpha anticorps

Épitope: C-Term

Specificité: Polyclonal antibody raised in rabbit against human RARA (Retinoic Acid Receptor alpha) using two KLH-conjugated synthetic peptides containing sequences from the C-terminal region of the protein.

Purification: whole antiserum

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP/ChIP-seq 4 μL:ChIP
ELISA 1:50
WB 1:750

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: serum, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Retinoic Acid Receptor alpha

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Autre désignation: RARA

Sujet: RARA (UniProtKB/Swiss-Prot entry P10276) is a receptor for retinoic acid, a vitamin A metabolite, which directly regulates gene expression in target cells by binding to specific DNA response elements. In the absence of its ligand, this receptor represses transcription through the recruitment of specific corepressors and of HDAC's, whereas binding of retinioc acid causes the recruitment of coactivators and HAT's. Translocations involving the RARA gene, often leading to a RARA/PML fusion protein, are a major cause of acute promyelocytic leukemia.

UniProt: P10276

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins