KDM5C anticorps

N° du produit ABIN6952407

L’anticorps anti-KDM5C Polyclonal produit chez le Lapin a été validé pour WB, IP, ChIP et ChIP-seq. Il convient pour la détection de KDM5C dans des échantillons provenant de Humain. }

Aperçu rapide pour KDM5C anticorps (ABIN6952407)

Antigène: KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM5C est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-KDM5C anticorps

Specificité: Polyclonal antibody raised in rabbit against human JARID1C (Jumonji, AT Rich Interactive Domain 1C), using a synthetic peptide containing a sequence from the central part of the protein

Réactivité croisée: Souris

Purification: Affinity purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP/ChIP-seq 5 μg:ChIP
WB 1:1,000
IP 6 μg:IP

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 μg/μL

Buffer: TBS, 0,1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur KDM5C

Antigène: KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))

Autre désignation: JARID1C

Sujet: JARID1C (UniProtKB/Swiss-Prot entry P41229) is a histone demethylase that specifically demethylates tri- and dimethylated Lys-4 of histone H3. It has no activity towards monomethylated H3K4, H3K9, H3K27, H3K36, H3K79 or H4K20. It is involved in transcriptional regulation and chromatin remodeling. JARID1C participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in JARID1C have been associated with X-linked mental retardation

UniProt: P41229

Pathways: L'effet Warburg