SARS-CoV-2 Spike S1 anticorps (RBD)
Aperçu rapide pour SARS-CoV-2 Spike S1 anticorps (RBD) (ABIN6952746)
Antigène
Voir toutes SARS-CoV-2 Spike S1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- RBD
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Fonction
- Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Spike Protein S1 Receptor Binding Domain
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Specificité
- This antibody was selected for its ability to bind to the virus SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) from the disease COVID-19.
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Attributs du produit
- Rabbit anti-SARS-CoV-2 S1 RBD antibody
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Purification
- The IgG fraction was purified by Protein A affinity chromatography.
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Immunogène
- This antibody was produced from antiserum of rabbits immunized with a recombinant SARS-CoV-2 S1 RBD protein.
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Isotype
- IgG
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Indications d'application
- ELISA (recommended work dilution = 1:160,000)
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute the antibody with sterile water to a final concentration of 1 mg/mL.
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Buffer
- Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution.
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Conseil sur la manipulation
- Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.
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Stock
- -20 °C
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Stockage commentaire
- Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for at least 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C.
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: "Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. ..." dans: Molecular therapy : the journal of the American Society of Gene Therapy, (2021) (PubMed).
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: "Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. ..." dans: Molecular therapy : the journal of the American Society of Gene Therapy, (2021) (PubMed).
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- SARS-CoV-2 Spike S1
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Classe de substances
- Viral Protein
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Sujet
- It's been reported that 2019-nCoV (COVID-19) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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ID gène
- 43740568
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UniProt
- P0DTC2
Antigène
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