Perforin 1 anticorps

N° du produit ABIN6963873

L’anticorps Souris Monoclonal anti-Perforin 1 a été validé pour ELISA et ELISpot. Il convient pour détecter Perforin 1 dans des échantillons de Humain et Non-Human Primate. Il y a 5+ publications disponibles.

Aperçu rapide pour Perforin 1 anticorps (ABIN6963873)

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Perforin 1 est non-conjugé

Application: ELISA, ELISpot

Clone: Pf-80-164

Détail du produit anti-Perforin 1 anticorps

Specificité: Native Perforin.

Réactivité croisée (Details): The monoclonal antibody cross-reacts with Perforin from non-human primates.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Native human Perforin

Isotype: IgG1

Information d'application

Indications d'application: For quantification of Perforin in solution e.g. cell culture supernatants using ELISA and for enumeration of Perforin producing cells using ELISpot. Pf-80/164 is recommended as coating mAb in combination with detection mAb Pf-344 .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store product at 4-8°C.

Date de péremption: 18 months

Références pour anticorps anti-Perforin 1 (ABIN6963873)

Hu, Valentin, Cai, Dayton, Rosati, Ramírez-Salazar, Kulkarni, Broderick, Sardesai, Wyatt, Earl, Moss, Mullins, Pavlakis, Felber: "DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination." dans: Human gene therapy, Vol. 29, Issue 9, pp. 1029-1043, (2019) (PubMed).

Parrot, Allard, Oger, Benlalam, Raingeard de la Blétière, Coutolleau, Preisser, Desfrançois, Khammari, Dréno, Labarrière, Delneste, Guardiola, Gervois: "IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive T cells." dans: European journal of immunology, Vol. 46, Issue 7, pp. 1770-82, (2017) (PubMed).

Rout: "Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques." dans: PLoS ONE, Vol. 11, Issue 6, pp. e0157407, (2017) (PubMed).

Chung, Hung, Yang, Su, Huang, Wei, Chin, Chiou, Chu, Ho, Yang, Lu, Wu, Liao, Chen: "Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis." dans: Nature medicine, Vol. 14, Issue 12, pp. 1343-50, (2008) (PubMed).

Belyakov, Kuznetsov, Kelsall, Klinman, Moniuszko, Lemon, Markham, Pal, Clements, Lewis, Strober, Franchini, Berzofsky: "Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa." dans: Blood, Vol. 107, Issue 8, pp. 3258-64, (2006) (PubMed).

Détails sur Perforin 1

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Autre désignation: Perforin

ID gène: 5551

Pathways: Apoptose, Caspase Cascade in Apoptosis