IL-21 anticorps

N° du produit ABIN6963915

Il existe 4+ publications pour ce produit. L’anticorps anti-IL-21 Monoclonal Souris est utilisé pour la détection de IL-21 dans des échantillons de Humain et Non-Human Primate. Il a été validé pour ELISA et ELISpot.

Aperçu rapide pour IL-21 anticorps (ABIN6963915)

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-21 est non-conjugé

Application: ELISA, ELISpot

Clone: MT216G

Détail du produit anti-IL-21 anticorps

Specificité: Native and recombinant IL-21

Réactivité croisée (Details): The monoclonal antibody cross-reacts with IL-21 from non-human primates.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant human IL-21

Isotype: IgG1

Information d'application

Indications d'application: For quantification of IL-21 in solution e.g. cell culture supernatants using ELISA and for enumeration of IL-21 producing cells using ELISpot. MT216G is recommended as coating mAb in combination with detection mAb MT21.3m .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-IL-21 (ABIN6963915)

Yamamoto, Kitawaki, Sugimoto, Fujita, Kawase, Takaori-Kondo, Kadowaki: "Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide." dans: Immunology letters, Vol. 211, pp. 41-48, (2020) (PubMed).

Laestadius, Ingelman-Sundberg, Myrberg, Verme, Sundberg, Schweiger, Saghafian-Hedengren, Nilsson: "Altered proportions of circulating CXCR5+ helper T cells do not dampen influenza vaccine responses in children with rheumatic disease." dans: Vaccine, Vol. 37, Issue 28, pp. 3685-3693, (2020) (PubMed).

Zhou, Tong, Guan, Li, Feng, Zhou, Zhang: "Circulating follicular helper T cells presented distinctively different responses toward bacterial antigens in primary biliary cholangitis." dans: International immunopharmacology, Vol. 51, pp. 76-81, (2018) (PubMed).

Hennerici, Pollmann, Schmidt, Seipelt, Tackenberg, Möbs, Ghoreschi, Hertl, Eming: "Increased Frequency of T Follicular Helper Cells and Elevated Interleukin-27 Plasma Levels in Patients with Pemphigus." dans: PLoS ONE, Vol. 11, Issue 2, pp. e0148919, (2016) (PubMed).

Détails sur IL-21

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: IL21

ID gène: 59067

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response