APOE anticorps

N° du produit ABIN6963954

Il existe 2+ publications pour ce produit. L’anticorps anti-APOE Monoclonal Rat est utilisé pour la détection de APOE dans des échantillons de Souris. Il a été validé pour ELISA.

Aperçu rapide pour APOE anticorps (ABIN6963954)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp APOE est non-conjugé

Application: ELISA

Clone: ME1

Détail du produit anti-APOE anticorps

Specificité: Apolipoprotein E

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant mouse apoE

Isotype: IgG2a

Information d'application

Indications d'application: For quantification of mouse apoE in solution e.g. serum/plasma samples and cell culture supernatants using ELISA. mE1 is recommended as coating mAb in combination with biotinylated detection mAb mE29 .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-APOE (ABIN6963954)

Gordon, Yao, Xu, Karkowsky, Kaler, Kalchiem-Dekel, Barochia, Gao, Keeran, Jeffries, Levine: "Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects." dans: The Journal of allergy and clinical immunology, Vol. 144, Issue 2, pp. 426-441.e3, (2020) (PubMed).

Centa, Prokopec, Garimella, Habir, Hofste, Stark, Dahdah, Tibbitt, Polyzos, Gisterå, Johansson, Maeda, Hansson, Ketelhuth, Coquet, Binder, Karlsson, Malin: "Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 8, pp. e145-e158, (2019) (PubMed).

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: apoE

ID gène: 11816

Pathways: Regulation of Cell Size, Lipid Metabolism