APOE anticorps (Biotin)

N° du produit ABIN6963955

Cet anticorps anti-APOE est un anticorps Rat Monoclonal détectant APOE dans WB et ELISA. Adapté pour Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour APOE anticorps (Biotin) (ABIN6963955)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp APOE est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Clone: ME29

Détail du produit anti-APOE anticorps (Biotin)

Specificité: Apolipoprotein E

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant mouse apoE

Isotype: IgG2a

Information d'application

Indications d'application: For quantification of mouse apoE in serum/plasma samples and cell culture supernatants using ELISA. mE29 is recommended as detection mAb in combination with coating mAb mE1 . The antibody is also suitable for immunoprecipitation and Western blot.

Commentaires:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-APOE (Biotin) (ABIN6963955)

Gordon, Yao, Xu, Karkowsky, Kaler, Kalchiem-Dekel, Barochia, Gao, Keeran, Jeffries, Levine: "Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects." dans: The Journal of allergy and clinical immunology, Vol. 144, Issue 2, pp. 426-441.e3, (2020) (PubMed).

Centa, Prokopec, Garimella, Habir, Hofste, Stark, Dahdah, Tibbitt, Polyzos, Gisterå, Johansson, Maeda, Hansson, Ketelhuth, Coquet, Binder, Karlsson, Malin: "Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 8, pp. e145-e158, (2019) (PubMed).

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: apoE

ID gène: 11816

Pathways: Regulation of Cell Size, Lipid Metabolism