IL-21 anticorps (Biotin)

N° du produit ABIN6964032

L’anticorps Souris Monoclonal anti-IL-21 a été validé pour ELISA. Il convient pour détecter IL-21 dans des échantillons de Humain et Non-Human Primate. Il y a 5+ publications disponibles.

Aperçu rapide pour IL-21 anticorps (Biotin) (ABIN6964032)

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-21 est conjugé à/à la Biotin

Application: ELISA

Clone: MT21-3m

Détail du produit anti-IL-21 anticorps (Biotin)

Specificité: Native and recombinant human IL-21

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant human IL-21

Isotype: IgG1

Information d'application

Indications d'application: To retain detectable levels of IL-21 in cell culture supernatants, biotinylated mAb MT21.3m can be included during cell culture. The antibody will bind to secreted IL-21 thus preventing IL-21 from interacting with its receptor. In this way, IL-21 is kept in solution and can be quantified in ELISA. For this purpose, MT21.3m is free of preservatives. Please note that mAb MT21.3m is optimized for use with human IL-21 ELISA kits and anti-human IL-21 mAbs from Mabtech.

Commentaires:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS free of preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-IL-21 (Biotin) (ABIN6964032)

Laestadius, Ingelman-Sundberg, Myrberg, Verme, Sundberg, Schweiger, Saghafian-Hedengren, Nilsson: "Altered proportions of circulating CXCR5+ helper T cells do not dampen influenza vaccine responses in children with rheumatic disease." dans: Vaccine, Vol. 37, Issue 28, pp. 3685-3693, (2020) (PubMed).

Yamamoto, Kitawaki, Sugimoto, Fujita, Kawase, Takaori-Kondo, Kadowaki: "Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide." dans: Immunology letters, Vol. 211, pp. 41-48, (2020) (PubMed).

Lasaviciute, Björkander, Carvalho-Queiroz, Hed Myrberg, Nussbaum, Nilsson, Bemark, Nilsson, Sverremark-Ekström, Saghafian-Hedengren: "Epstein-Barr Virus, but Not Cytomegalovirus, Latency Accelerates the Decay of Childhood Measles and Rubella Vaccine Responses-A 10-Year Follow-up of a Swedish Birth Cohort." dans: Frontiers in immunology, Vol. 8, pp. 1865, (2017) (PubMed).

Amu, Lantto Graham, Bekele, Nasi, Bengtsson, Rethi, Sorial, Meini, Zazzi, Hejdeman, Chiodi: "Dysfunctional phenotypes of CD4+ and CD8+ T cells are comparable in patients initiating ART during early or chronic HIV-1 infection." dans: Medicine, Vol. 95, Issue 23, pp. e3738, (2017) (PubMed).

Huang, Ehrnfelt, Paulie, Zuber, Ahlborg: "ELISpot and ELISA analyses of human IL-21-secreting cells: Impact of blocking IL-21 interaction with cellular receptors." dans: Journal of immunological methods, Vol. 417, pp. 60-66, (2015) (PubMed).

Détails sur IL-21

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: IL21

ID gène: 59067

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response