CENPA anticorps (pSer16, pSer18)

N° du produit ABIN6971521

Détail du produit anti-CENPA anticorps

Antigène: CENPA (Centromere Protein A (CENPA))

Épitope: pSer16, pSer18

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

Attributs du produit: CENP-A (Centromere Protein A) is a Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. It is required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. Recently, phosphorylation of CENP-A on Ser16 and Ser18 was reported and found to be important for chromosome segregation during mitosis. CENP-A phospho Ser18 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Dot blot, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human samples, but it is predicted that it will react with a wide range of sample types.

Purification: Affinity Purified

Immunogène: This antibody was raised against a synthetic peptide containing phosphorylated serine 16 and 18 of human CENP-A.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur CENPA

Antigène: CENPA (Centromere Protein A (CENPA))

Autre désignation: CENP-A (CENPA Produits)

Synonymes: anticorps CENP-A, anticorps CenH3, anticorps Cenp-A, anticorps cenpx, anticorps cenp-a, anticorps sim2, anticorps Cenp-a, anticorps RGD1563607, anticorps CENPA, anticorps centromere protein A, anticorps centromere protein-A, anticorps centromeric histone-3 like protein, anticorps centromere-specific histone H3 CENP-A, anticorps cenp-A, anticorps centromere protein A L homeolog, anticorps histone H3-like centromeric protein A, anticorps CENPA, anticorps Cenpa, anticorps CENP-A, anticorps cenpa, anticorps cenp-A, anticorps cnp1, anticorps HAN_3g422, anticorps Cenp-a, anticorps cenpa.L, anticorps CMU_016480

Poids moléculaire: 16 kDa

NCBI Accession: NP_001800

Pathways: Chromatin Binding, Maintenance of Protein Location