Estrogen Receptor alpha anticorps (C-Term)

N° du produit ABIN6971631

L’anticorps anti-Estrogen Receptor alpha Monoclonal Souris est utilisé pour la détection de Estrogen Receptor alpha dans des échantillons de Humain. Il a été validé pour WB, IP et ChIP.

Aperçu rapide pour Estrogen Receptor alpha anticorps (C-Term) (ABIN6971631)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Clone: F3

Détail du produit anti-Estrogen Receptor alpha anticorps

Épitope: C-Term

Attributs du produit: ER-a (estrogen receptor a) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding and activation of transcription. ER-a localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer and osteoporosis. Estrogen Receptor alpha antibody (mAb) (Clone F3) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation, Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Purification: Protein G Chromatography

Immunogène: This ER-alpha antibody was raised against a peptide within the C-terminal region of human Estrogen Receptor alpha.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: Estrogen Receptor α

Poids moléculaire: 66 kDa

NCBI Accession: NP_000116

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly