CHD4 anticorps
Aperçu rapide pour CHD4 anticorps (ABIN6972352)
Antigène
Voir toutes CHD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Mi-2b (Mi-2beta, CHD4, chromodomain helicase DNA-binding protein 4) represents the major Mi-2 isoform present in the complex Mi-2/NuRD. This complex is a multi-subunit protein complex containing both histone deacetylase and nucleosome-dependent ATPase subunits. Current models predict that this complex functions primarily in transcriptional repression. In addition to the ATPase domain, Mi-2 beta contains a chromodomain and two PHD domains. Mi-2 beta interacts with BRG-1, a component of the SWI/SNF complex, and the RET finger protein (RFP). Mi-2 beta antibody (mAb) (Clone 3F2/4) was raised in a Mouse host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.
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Purification
- Protein G Chromatography
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Immunogène
- This Mi-2 beta antibody was raised against a synthetic peptide derived from human Mi-2B.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))
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Autre désignation
- Mi-2 beta
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Poids moléculaire
- 240 kDa
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NCBI Accession
- NP_001264
Antigène
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