PAX6 anticorps (C-Term)
Aperçu rapide pour PAX6 anticorps (C-Term) (ABIN6972491)
Antigène
Voir toutes PAX6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Attributs du produit
- PAX6 (Paired Box 6) is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes. PAX6 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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Purification
- Affinity Purified
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Immunogène
- This antibody was raised against a peptide within the C-terminal region of human PAX6.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- PAX6 (Paired Box 6 (PAX6))
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Autre désignation
- PAX6
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Poids moléculaire
- 52 kDa
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NCBI Accession
- NP_001595
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Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
Antigène
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