RAR-alpha (AA 420-443) anticorps

N° du produit ABIN6972582

L’anticorps anti-RAR-alpha Monoclonal Souris est utilisé pour la détection de RAR-alpha dans des échantillons de Humain et Souris. Il a été validé pour IHC, SSA et WB.

Aperçu rapide pour RAR-alpha (AA 420-443) anticorps (ABIN6972582)

Antigène: RAR-alpha

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), Supershift Assay (SSA), Western Blotting (WB)

Clone: 9alpha-9A6

Détail du produit

Épitope: AA 420-443

Attributs du produit: Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-a (Nuclear receptor subfamily 1 group B member 1, NR1B1) interacts with NCoA3, NCoA6, NCoA7 and MLL to activate transcription of target genes. Chromosomal aberrations of RAR-a are sometimes involved in Promyelocytic leukemia. RAR-alpha antibody (mAb) (Clone 9a-9A6) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Supershift and Western blot, it has been shown to react with Human and Mouse samples.

Purification: Protein A Chromatography

Immunogène: This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 60 mM Sodium Citrate, 105 mM Tris-HCl, 30 % glycerol, and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détail du antigène

Antigène: RAR-alpha

Autre désignation: RAR-α

Poids moléculaire: 52 kDa

NCBI Accession: NP_001138773