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SOX2 anticorps (C-Term)

SOX2 Reactivité: Humain, Souris WB, IF, ICC, CUT&RUN, ChIP-seq, ChIP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6972778
  • Antigène Voir toutes SOX2 Anticorps
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Épitope
    • 17
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 10
    • 10
    • 10
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    • 7
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 204
    • 98
    • 68
    • 21
    • 13
    • 10
    • 10
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 162
    • 46
    • 2
    Lapin
    Clonalité
    • 161
    • 49
    Polyclonal
    Conjugué
    • 100
    • 16
    • 15
    • 11
    • 10
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SOX2 est non-conjugé
    Application
    • 161
    • 108
    • 50
    • 44
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    • 40
    • 28
    • 24
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    • 17
    • 15
    • 12
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    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Cleavage Under Targets and Release Using Nuclease (CUT&RUN), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP)
    Attributs du produit
    Sox2 (SRY related HMG BOX gene 2) is a DNA binding transcription factor and a member of the SOX family of proteins. SOX proteins have an HMG box that binds DNA. Sox2 forms a complex with Oct-4 and controls the expression of a number of genes involved in embryonic. Sox2 is critical for early embryogenesis and for embryonic stem cell pluripotency and thus can serve as a stem cell marker. Overexpression of Sox2 (along with Oct-4, KLF4 and c-Myc) can transform mouse fibroblasts into a state resembling embryonic stem cells (ES cells), referred to as Induced Pluripotency. Defects in Sox2 are the cause of microphthalmia syndromic type 3. Sox2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    Purification
    Affinity Purified
    Immunogène
    This Sox2 antibody was raised against a peptide within the C-terminal region of human Sox2.
    Isotype
    IgG
    Top Product
    Discover our top product SOX2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Janssens, Wu, Sarthy, Meers, Myers, Olson, Ahmad, Henikoff: "Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs." dans: Epigenetics & chromatin, Vol. 11, Issue 1, pp. 74, (2019) (PubMed).

  • Antigène
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Autre désignation
    Sox2 (SOX2 Produits)
    Synonymes
    anticorps ANOP3, anticorps MCOPS3, anticorps RGD1565646, anticorps Sox-2, anticorps lcc, anticorps ysb, anticorps cb236, anticorps wu:fb83g04, anticorps wu:fc14d07, anticorps zgc:65860, anticorps zgc:77389, anticorps SRY-box2, anticorps Xsox-2, anticorps anop3, anticorps mcops3, anticorps sox-2, anticorps SRY-box 2, anticorps SRY box 2, anticorps SRY (sex determining region Y)-box 2, anticorps SRY-box 2 S homeolog, anticorps SOX2, anticorps Sox2, anticorps sox2, anticorps sox2.S
    Poids moléculaire
    42 kDa
    NCBI Accession
    NP_003097
    Pathways
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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