CD209b Antigen (CD209B) (AA 51-150) anticorps (AbBy Fluor® 350)

N° du produit ABIN6976684

Cet anticorps Lapin Polyclonal détecte spécifiquement dans WB, IF (cc) et IF (p). Il présente une réactivité envers Souris.

Aperçu rapide pour CD209b Antigen (CD209B) (AA 51-150) anticorps (AbBy Fluor® 350) (ABIN6976684)

Antigène: CD209b Antigen (CD209B)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 51-150

Réactivité croisée: Souris

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CD209b

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CD209b Antigen (CD209B)

Autre désignation: CD209b

Sujet:

Synonyms: SIGN Related 1, CD209 antigen like protein B, CD209b antigen, DC SIGN related protein 1, DC SIGNR1, OtB7

Background: SIGN R1 is a specific marker for the identification of macrophage subpopulations present in the marginal zone of spleen (the so-called marginal zone macrophages (MZM)), in the lymph node medulla, and in some strains, in the peritoneal cavity. MZM of the spleen are involved in the clearance of polysaccharides. Mouse SIGN R1 is a C type lectin, like DC SIGN which is expressed on Human dendritic cells (DCs). However, Mmouse SIGN R1 itself is not expressed on DCs. SIGN R1 exists in an aggregated form, resistant to dissociation into monomers upon boiling in SDS under reducing conditions. SIGN R1 mediates the uptake of encapsulated organisms and may be an important mediator for the uptake of microbes in both spleen and lymph node, particularly through the recognition of microbial polysaccharides.

ID gène: 69165

UniProt: Q8CJ91