CD27 anticorps (AA 101-200) (AbBy Fluor® 350)
Aperçu rapide pour CD27 anticorps (AA 101-200) (AbBy Fluor® 350) (ABIN6977103)
Antigène
Voir toutes CD27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-200
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Homologie
- Mouse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human CD27
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- CD27 (CD27 Molecule (CD27))
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Autre désignation
- CD27
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Sujet
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Synonyms: CD 27, Cd27, CD27 antigen, CD27 Molecule, CD27_MOUSE, CD27L receptor, LPFS2, MGC20393, OTTHUMP00000238557, S152, T cell activation antigen CD27, T cell antivation antigen S152, T-cell activation antigen CD27, T14, TNFRSF 7, TNFRSF7, TNFSF7, Tp 55, Tp55, Tumor necrosis factor receptor superfamily member 7.
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
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ID gène
- 21940
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UniProt
- P41272
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Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Antigène
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