DAPK3 anticorps (pThr265) (AbBy Fluor® 680)
Aperçu rapide pour DAPK3 anticorps (pThr265) (AbBy Fluor® 680) (ABIN6981512)
Antigène
Voir toutes DAPK3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- pThr265
-
Réactivité croisée
- Souris, Rat
-
Homologie
- Human,Dog,Cow,Pig,Horse
-
Purification
- Purified by Protein A.
-
Immunogène
- KLH conjugated synthesised phosphopeptide derived from human ZIP Kinase around the phosphorylation site of Thr265
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Date de péremption
- 12 months
-
-
- DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
-
Autre désignation
- ZIP Kinase
-
Sujet
-
Synonyms: Death-associated protein kinase 3, DAPK3, DAP kinase 3, Dlk, MYPT1 kinase, Zipper-interacting protein kinase, ZIP-kinase, ZIPK
Background: Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection.
-
ID gène
- 1613
-
UniProt
- O43293
Antigène
-