SBNO1 anticorps (AA 331-430) (AbBy Fluor® 750)

N° du produit ABIN6981913

Cet anticorps Lapin Polyclonal détecte spécifiquement SBNO1 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour SBNO1 anticorps (AA 331-430) (AbBy Fluor® 750) (ABIN6981913)

Antigène: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SBNO1 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SBNO1 anticorps (AbBy Fluor® 750)

Épitope: AA 331-430

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SBNO1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SBNO1

Antigène: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Autre désignation: SBNO1

Sujet:

Synonyms: FLJ10701, FLJ10833, FLJ16176, Monocyte protein 3, MOP 3, MOP-3, MOP3, Protein strawberry notch homolog 1, SBNO 1, Sbno1, SBNO1_HUMAN, Sno, Sno strawberry notch homolog 1, Strawberry notch homolog 1.

Background: SBNO1 is a 1,392 amino acid protein encoded by the human gene of the same name located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

ID gène: 55206

UniProt: A3KN83

Pathways: SARS-CoV-2 Protein Interactome