MCFD2 anticorps (AA 1-100) (Biotin)

N° du produit ABIN6982994

L’anticorps Lapin Polyclonal anti-MCFD2 a été validé pour WB, IHC (p) et IHC (fro). Il convient pour détecter MCFD2 dans des échantillons de Rat et Souris.

Aperçu rapide pour MCFD2 anticorps (AA 1-100) (Biotin) (ABIN6982994)

Antigène: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCFD2 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MCFD2 anticorps (Biotin)

Épitope: AA 1-100

Réactivité croisée: Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse MCFD2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MCFD2

Antigène: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Autre désignation: MCFD2

Sujet:

Synonyms: 1810021C21Rik, DKFZp686G21263, F5F8D, LMAN1IP, MCFD 2, Mcfd2, MCFD2_MOUSE, Multiple coagulation factor deficiency protein 2, Neural stem cell derived neuronal survival protein, Neural stem cell-derived neuronal survival protein, SDNSF.

Background: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010]

ID gène: 193813

UniProt: Q8K5B2