HMGB3 anticorps (Biotin)

N° du produit ABIN6983067

Cet anticorps anti-HMGB3 est un anticorps Lapin Polyclonal détectant HMGB3 dans IHC (p). Adapté pour Souris et Rat.

Aperçu rapide pour HMGB3 anticorps (Biotin) (ABIN6983067)

Antigène: HMGB3 (High Mobility Group Box 3 (HMGB3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGB3 est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HMGB3 anticorps (Biotin)

Réactivité croisée: Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HMG4/HMGB3:1-100/200

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur HMGB3

Antigène: HMGB3 (High Mobility Group Box 3 (HMGB3))

Autre désignation: HMG4/HMGB3

Sujet:

Synonyms: High mobility group (nonhistone chromosomal) protein 4, High mobility group box 3, High mobility group protein 2a, High mobility group protein 4, High mobility group protein B3, High mobility group protein HMG4, HMG 4, HMG-2a, HMG-4, HMG2A, HMGB 3, HMGB3, HMGB3_HUMAN, MGC90319, Non histone chromosomal protein, Nonhistone chromosomal protein HMG4.

Background: HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291], Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008] Function : Binds preferentially single-stranded DNA and unwinds double stranded DNA. Similarity : Belongs to the HMGB family. Contains 2 HMG box DNA-binding domains.

ID gène: 3149

UniProt: O15347