BTBD12 anticorps (AA 171-270) (Cy3)

N° du produit ABIN6983792

L’anticorps Lapin Polyclonal anti-BTBD12 a été validé pour IF (cc) et IF (p). Il convient pour détecter BTBD12 dans des échantillons de Souris.

Aperçu rapide pour BTBD12 anticorps (AA 171-270) (Cy3) (ABIN6983792)

Antigène: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTBD12 est conjugé à/à la Cy3

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-BTBD12 anticorps (Cy3)

Épitope: AA 171-270

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLX4/BTBD12

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BTBD12

Antigène: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Autre désignation: SLX4

Sujet:

Synonyms: BTB (POZ) domain containing 12, BTB/POZ domain-containing protein 12, BTBD12, FANCP, KIAA1784, KIAA1987, MUS312, SLX 4, slx4, SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae), SLX4_HUMAN, Structure-specific endonuclease subunit slx4.

Background: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq, Jan 2011]

ID gène: 84464

UniProt: Q8IY92

Pathways: Réparation de l'ADN