RHOC anticorps (AA 1-193)
Aperçu rapide pour RHOC anticorps (AA 1-193) (ABIN6989128)
Antigène
Voir toutes RHOC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-193
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Specificité
- KO-Validated
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Réactivité croisée
- Humain, Souris
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Homologie
- Rat
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Purification
- Purified by Protein A.
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RHOC (NP_001036144.1).
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(ICC) 1:50-200
IF() -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- RHOC (Ras Homolog Gene Family, Member C (RHOC))
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Autre désignation
- RHOC
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Sujet
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Synonyms: RHOC,ARH9,ARHC,H9,RHOH9
Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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ID gène
- 389
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UniProt
- P08134
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Pathways
- Signalisation WNT, Cell-Cell Junction Organization
Antigène
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