PAX6 anticorps (AA 221-320)

N° du produit ABIN6989341

Cet anticorps Lapin Polyclonal détecte spécifiquement PAX6 dans WB, ELISA, IHC (p), ICC, IF (p), IF (cc) et IHC (fro). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour PAX6 anticorps (AA 221-320) (ABIN6989341)

Antigène: PAX6 (Paired Box 6 (PAX6))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PAX6 anticorps

Épitope: AA 221-320

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PAX6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PAX6

Antigène: PAX6 (Paired Box 6 (PAX6))

Autre désignation: PAX6

Sujet:

Synonyms: AN 2, AN antibody, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, Paired box 6, Paired box gene 6 (aniridia keratitis), Paired Box Gene 6, Paired box homeotic gene 6, Paired box protein Pax-6, Paired box protein Pax6, PAX 6, PAX6, PAX6_HUMAN, Sey, WAGR.

Background: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

ID gène: 5080

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis