CD34 anticorps

N° du produit ABIN6989467

Cet anticorps Lapin Monoclonal détecte spécifiquement CD34 dans FACS et IHC (p). Il présente une réactivité envers Humain, Rat, Souris et Chien.

Aperçu rapide pour CD34 anticorps (ABIN6989467)

Antigène: CD34

Reactivité: Humain, Rat, Souris, Chien

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7A1

Détail du produit anti-CD34 anticorps

Réactivité croisée: Chien, Humain, Souris, Rat

Purification: Purified by Protein G.

Immunogène: Recombinant human CD34

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CD34

Antigène: CD34

Autre désignation: CD34

Sujet:

Synonyms: CD34 antigen, CD34 Molecule, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1, CD34_HUMAN.

Background: The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

ID gène: 947

UniProt: P28906