CD16 anticorps

N° du produit ABIN6989632

Cet anticorps Lapin Monoclonal détecte spécifiquement CD16 dans WB, IHC et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CD16 anticorps (ABIN6989632)

Antigène: CD16

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD16 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8F8

Détail du produit anti-CD16 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Synthetic Peptide within C-terminal human CD16.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CD16

Antigène: CD16

Autre désignation: CD16

Sujet:

Synonyms: CD 16 antibody, CD 16a antibody, CD16 antibody, CD16a antibody, CD16a antigen antibody, CD16B antibody, CD16b antigen antibody, Fc fragment of IgG antibody, Fc fragment of IgG low affinity IIIa receptor (CD16) antibody, Fc fragment of IgG low affinity IIIa receptor antibody, Fc fragment of IgG receptor IIIa antibody, Fc fragment of IgG, low affinity III, receptor (CD16) antibody, Fc fragment of IgG, low affinity III, receptor for (CD16) antibody

Background: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer(NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

ID gène: 2214

UniProt: P08637

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process