ATG4D anticorps

N° du produit ABIN6989740

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG4D dans WB et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ATG4D anticorps (ABIN6989740)

Antigène: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4D est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-ATG4D anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ATG4D (NP_116274.3).

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IF()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ATG4D

Antigène: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Autre désignation: ATG4D

Sujet:

Synonyms: ATG4D,APG4-D,APG4D,AUTL4

Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.

ID gène: 84971

UniProt: Q86TL0

Pathways: Autophagy