LY96 anticorps (C-Term)

N° du produit ABIN6990125

L’anticorps Lapin Polyclonal anti-LY96 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter LY96 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LY96 anticorps (C-Term) (ABIN6990125)

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LY96 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LY96 anticorps

Épitope: C-Term

Purification: MD-2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-MD-2 antibody was raised against a peptide corresponding to 13 amino acids near the center of human MD-2. The immunogen is located within the last 50 amino acids of MD-2.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.5-1 μ,g/mL, IHC: 2-2.5 μ,g/mL, IF: 10-20 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in human and rat samples, Immunofluorescence in human and rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MD-2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MD-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LY96

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Autre désignation: MD-2

Sujet: MD-2 Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2, e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

Poids moléculaire: Predicted: 19kD

Observed: 26 kD (Post-modification: 2 N-linked glycosylations) kDa

ID gène: 23643

NCBI Accession: NP_056179

UniProt: Q9Y6Y9

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades