PDCD1LG2 anticorps (AA 140-190)
Aperçu rapide pour PDCD1LG2 anticorps (AA 140-190) (ABIN6990126)
Antigène
Voir toutes PDCD1LG2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 140-190
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Purification
- PD-L2 Antibody is affinity chromatography purified via peptide column.
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Immunogène
- Anti-PD-L2 antibody was raised against a peptide corresponding to 16 amino acids near the center of human PD-L2. The immunogen is located within amino acids 140-190 of PD-L2.
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Isotype
- IgG
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Indications d'application
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WB: 0.5-4 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in mouse samples, Immunofluorescence in mouse samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PD-L2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- PD-L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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Autre désignation
- PD-L2
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Sujet
- PD-L2 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through and alternative receptor from PD-1.
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Poids moléculaire
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Predicted: 31kD
Observed: 29 kD kDa -
ID gène
- 80380
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NCBI Accession
- NP_079515
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UniProt
- Q9BQ51
Antigène
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