LY96 anticorps (AA 2-160)

N° du produit ABIN6990190

Cet anticorps Souris Monoclonal détecte spécifiquement LY96 dans WB, ELISA, ICC, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour LY96 anticorps (AA 2-160) (ABIN6990190)

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LY96 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1A2E3

Détail du produit anti-LY96 anticorps

Épitope: AA 2-160

Purification: MD-2 Monoclonal Antibody is Protein A purified.

Immunogène: Mouse monoclonal MD-2 antibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2.

Isotype: IgG1

Information d'application

Indications d'application: MD-2 antibody can be used for detection of MD-2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.

Antibody validated: Western Blot in recombinnat protein, Immunohistochemistry in human samples, Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MD-2 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: MD-2 monoclonal antibody can be stored at -20°C, stable for one year.

Détails sur LY96

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Autre désignation: MD-2

Sujet: MD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2, e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

ID gène: 23643

NCBI Accession: NP_056179

UniProt: Q9Y6Y9

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades