alpha Tubulin anticorps (C-Term)

N° du produit ABIN6990222

Cet anticorps anti-alpha Tubulin Monoclonal Souris (Clone 2B11) (ABIN6990222) détecte spécifiquement alpha Tubulin dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio) et Lapin.

Aperçu rapide pour alpha Tubulin anticorps (C-Term) (ABIN6990222)

Antigène: alpha Tubulin (TUBA1)

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp alpha Tubulin est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2B11

Détail du produit anti-alpha Tubulin anticorps

Épitope: C-Term

Specificité: Alpha-Tubulin antibody is human, mouse, rat, rabbit, and zebrafish reactive.

Purification: alpha-Tubulin antibody is affinity chromatography purified via peptide column.

Immunogène: alpha-Tubulin antibody was raised against an 18 amino acid peptide near the carboxy terminus of human alpha-Tubulin

Isotype: IgG

Information d'application

Indications d'application: alpha-Tubulin antibody can be used for detection of alpha-Tubulin by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: alpha-Tubulin antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: alpha-Tubulin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur alpha Tubulin

Antigène: alpha Tubulin (TUBA1)

Autre désignation: alpha-Tubulin

Sujet: Alpha-Tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-Tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter (reviewed in 1). Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-Tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase (2). Another post-translational modification of detyrosinated alpha-Tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle (3). Like GAPDH and ?-Actin, this antibody makes an excellent loading control in immunoblots.

Poids moléculaire: Predicted: 50 kDa

Observed: 54 kDa

ID gène: 7846

Pathways: Dynamique des Microtubules