DAPK3 anticorps (AA 270-320)

N° du produit ABIN6990278

Détail du produit anti-DAPK3 anticorps

Antigène: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Épitope: AA 270-320

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAPK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: ZIPK Antibody is affinity chromatography purified via peptide column.

Immunogène: ZIP kinase antibody was raised against a peptide corresponding to amino acids near the center of human ZIP kinase. The immunogen is located within amino acids 270 - 320 of ZIPK.

Isotype: IgG

Information d'application

Indications d'application: ZIPK antibody can be used for detection of DNase II expression by Western blot at 1 μ,g/mL. An approximate 40 kDa band can be detected, which represents the pro-enzyme of DNase II. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZIPK Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZIPK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DAPK3

Antigène: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Autre désignation: ZIPK (DAPK3 Produits)

Synonymes: anticorps DAPK3, anticorps dapk3, anticorps wu:fc25b08, anticorps si:dkey-57k2.5, anticorps MGC114871, anticorps ZIP, anticorps ZIPK, anticorps dlk, anticorps Dapkl, anticorps death associated protein kinase 3, anticorps death-associated protein kinase 3, anticorps death-associated protein kinase 3 L homeolog, anticorps DAPK3, anticorps dapk3, anticorps dapk3.L, anticorps Dapk3

Sujet: ZIPK Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.

Poids moléculaire: Predicted: 26 kDa

Observed: 27 kDa

ID gène: 1613

UniProt: O43293