ACIN1 anticorps (AA 760-810)

N° du produit ABIN6990317

L’anticorps Lapin Polyclonal anti-ACIN1 a été validé pour WB, ELISA, ICC et IF. Il convient pour détecter ACIN1 dans des échantillons de Humain.

Aperçu rapide pour ACIN1 anticorps (AA 760-810) (ABIN6990317)

Antigène: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACIN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-ACIN1 anticorps

Épitope: AA 760-810

Purification: Acinus Antibody is affinity chromatography purified via peptide column.

Immunogène: Acinus antibody was raised against a 35 amino acid peptide near the center of human Acinus. The immunogen is located within amino acids 760 - 810 of Acinus.

Isotype: IgG

Information d'application

Indications d'application: Acinus antibody can be used for detection of Acinus by Western blot at 1 μ,g/mL. A 220 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Acinus Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Acinus antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ACIN1

Antigène: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Autre désignation: Acinus

Sujet: Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.

Poids moléculaire: 220 kDa

ID gène: 22985

UniProt: Q9UKV3