IL27 Receptor alpha anticorps (C-Term)

N° du produit ABIN6990378

Cet anticorps anti-IL27 Receptor alpha est un anticorps Lapin Polyclonal détectant IL27 Receptor alpha dans WB, ELISA, IHC (p) et IF. Adapté pour Humain.

Aperçu rapide pour IL27 Receptor alpha anticorps (C-Term) (ABIN6990378)

Antigène: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL27 Receptor alpha est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-IL27 Receptor alpha anticorps

Épitope: C-Term

Purification: TCCR Antibody is affinity chromatography purified via peptide column.

Immunogène: TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor. The sequence is identical to that of mouse TCCR. The immunogen is located within the last 50 amino acids of TCCR.

Isotype: IgG

Information d'application

Indications d'application: TCCR antibody can be used for detection of TCCR by Western blot at 1 μ,g/mL. An approximately 70 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TCCR Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TCCR antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IL27 Receptor alpha

Antigène: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Autre désignation: TCCR

Sujet: TCCR Antibody: Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.

Poids moléculaire: 70 kDa

ID gène: 9466

NCBI Accession: NP_004834

UniProt: Q6UWB1

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response