KAP1 anticorps (C-Term)
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- Antigène Voir toutes KAP1 (TRIM28) Anticorps
- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KAP1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- At least three isoforms of TRIM28 are known to exist, this antibody will detect all three isoforms
- Purification
- TRIM28 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- Rabbit polyclonal TRIM28 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TRIM28. The immunogen is located within the last 50 amino acids of TRIM28.
- Isotype
- IgG
- Top Product
- Discover our top product TRIM28 Anticorps primaire
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- Indications d'application
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TRIM28 antibody can be used for detection of TRIM28 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- TRIM28 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- TRIM28 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
- Autre désignation
- TRIM28 (TRIM28 Produits)
- Synonymes
- anticorps KAP1, anticorps RNF96, anticorps TF1B, anticorps TIF1B, anticorps TRIM28, anticorps kap1, anticorps rnf96, anticorps tf1b, anticorps tif1b, anticorps AA408787, anticorps KAP-1, anticorps KRIP-1, anticorps Tif1b, anticorps Tif1beta, anticorps Kap1, anticorps Krip1, anticorps TIF1BETA, anticorps tripartite motif containing 28, anticorps tripartite motif containing 28 L homeolog, anticorps tripartite motif-containing 28, anticorps TRIM28, anticorps trim28.L, anticorps Trim28
- Sujet
- TRIM28 Antibody: TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation.
- Poids moléculaire
- Predicted: 92 kDa
- ID gène
- 10155
- NCBI Accession
- NP_005753
- UniProt
- Q13263
- Pathways
- Signalisation Hedgehog, Positive Regulation of Response to DNA Damage Stimulus
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