TLR7 anticorps (AA 420-470)

N° du produit ABIN6990451

Détail du produit anti-TLR7 anticorps

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Épitope: AA 420-470

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: TLR7 Antibody is affinity chromatography purified via peptide column.

Immunogène: TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the center of mouse TLR7. The immunogen is located within amino acids 420 - 470 of TLR7.

Isotype: IgG

Information d'application

Indications d'application: TLR7 antibody can be used for detection of TLR7 by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLR7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TLR7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TLR7

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Autre désignation: TLR7 (TLR7 Produits)

Synonymes: anticorps TLR7-like, anticorps RGD1563357, anticorps toll like receptor 7, anticorps toll-like receptor 7, anticorps TLR7, anticorps Tlr7

Sujet: TLR7 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.

Poids moléculaire: Predicted: 116 kDa

Observed: 135 kDa

ID gène: 170743

NCBI Accession: NP_573474

UniProt: P58681

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades