BCL2L1 anticorps (C-Term)

N° du produit ABIN6990472

Cet anticorps Lapin Polyclonal détecte spécifiquement BCL2L1 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour BCL2L1 anticorps (C-Term) (ABIN6990472)

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BCL2L1 anticorps

Épitope: C-Term

Purification: Bcl-xL Antibody is supplied as ion exchange chromatography purified IgG.

Immunogène: Bcl-xL antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bcl-xL. The immunogen is located within the last 50 amino acids of Bcl-xL.

Isotype: IgG

Information d'application

Indications d'application: Bcl-xL antibody can be used for detection of Bcl-xL by Western blot at 1 to 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Bcl-xL Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Bcl-xL antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BCL2L1

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Autre désignation: Bcl-xL

Sujet: Bcl-xL Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene. Its high expression in tumors is correlated with advanced disease and poor prognosis. Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents.

ID gène: 598

UniProt: Q07817

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling