CASP5 anticorps (N-Term)

N° du produit ABIN6990516

Cet anticorps anti-CASP5 Polyclonal Lapin (ABIN6990516) détecte spécifiquement CASP5 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CASP5 anticorps (N-Term) (ABIN6990516)

Antigène: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASP5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CASP5 anticorps

Épitope: AA 40-90, N-Term

Specificité: Depending on cell lines or tissues used, other cleavage products may be observed.

Purification: Caspase-5 Antibody is affinity chromatography purified via peptide column.

Immunogène: Caspase-5 antibody was raised against a 16 amino acid synthetic peptide from the amino-terminus of human Caspase-5. The immunogen is located within amino acids 40 - 90 of Caspase-5.

Isotype: IgG

Information d'application

Indications d'application: Casp-5 antibody can be used for the detection of Caspase-5 by Western blot at 0.5 to 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Caspase-5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Caspase-5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CASP5

Antigène: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Autre désignation: Caspase-5

Sujet: Caspase-5 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1β, and IL-18. Caspase-5 can interact with caspase-1, both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1β,. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.

Poids moléculaire: Predicted: 48 kDa

Observed: 48 kDa

ID gène: 838

UniProt: P51878

Pathways: Inflammasome