TLR3 anticorps (N-Term)

N° du produit ABIN6990586

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR3 dans WB, ELISA, ICC et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TLR3 anticorps (N-Term) (ABIN6990586)

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-TLR3 anticorps

Épitope: AA 40-90, N-Term

Purification: TLR3 Antibody is affinity chromatography purified via peptide column.

Immunogène: TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR3. The immunogen is located within amino acids 40 - 90 of TLR3.

Isotype: IgG

Information d'application

Indications d'application: TLR3 antibody can be used for detection of TLR3 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TLR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TLR3

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Autre désignation: TLR3

Sujet: TLR3 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection. Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.

Poids moléculaire: Predicted: 88 kDa

Observed: 91 kDa

ID gène: 7098

UniProt: O15455

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades