TIMD4 anticorps (AA 60-110)

N° du produit ABIN6990640

Cet anticorps Lapin Polyclonal détecte spécifiquement TIMD4 dans ELISA, WB, IF, IHC (p) et ICC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TIMD4 anticorps (AA 60-110) (ABIN6990640)

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMD4 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-TIMD4 anticorps

Épitope: AA 60-110

Specificité: At least four isoforms of TIM-4 are known to exist, this antibody will detect all four isoforms.

Purification: TIM-4 Antibody is affinity chromatography purified via peptide column.

Immunogène: TIM-4 antibody was raised against a 16 amino acid synthetic peptide from near the center of human TIM-4. The immunogen is located within amino acids 60 - 110 of TIM-4.

Isotype: IgG

Information d'application

Indications d'application: TIM-4 antibody can be used for the detection of TIM-4 by Western blot at 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL and Immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TIM-4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TIM-4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TIMD4

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Autre désignation: TIM-4

Sujet: TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Poids moléculaire: Observed: 45 kDa

ID gène: 91937

NCBI Accession: NP_612388

UniProt: Q96H15

Pathways: Cancer Immune Checkpoints