FAF1 anticorps (C-Term)
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- Antigène Voir toutes FAF1 Anticorps
- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FAF1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- FAF1 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- FAF1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAF1. The immunogen is located within the last 50 amino acids of FAF1.
- Isotype
- IgG
- Top Product
- Discover our top product FAF1 Anticorps primaire
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- Indications d'application
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FAF1 antibody can be used for detection of FAF1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- FAF1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- FAF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
- Autre désignation
- FAF1 (FAF1 Produits)
- Synonymes
- anticorps faf1, anticorps MGC53741, anticorps MGC80303, anticorps FAF1, anticorps zgc:55752, anticorps wu:fc25h12, anticorps HFAF1s, anticorps UBXD12, anticorps UBXN3A, anticorps hFAF1, anticorps AA408698, anticorps Dffrx, anticorps Fam, anticorps Fas (TNFRSF6) associated factor 1 S homeolog, anticorps Fas (TNFRSF6) associated factor 1 L homeolog, anticorps Fas associated factor 1, anticorps Fas (TNFRSF6) associated factor 1, anticorps Fas-associated factor 1, anticorps faf1.S, anticorps faf1.L, anticorps FAF1, anticorps faf1, anticorps Faf1
- Sujet
- FAF1 Antibody: Fas-associated protein 1 (FAF1) was initially identified as a Fas-binding pro-apoptotic protein that is component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 can also induce apoptosis in the absence of extrinsic death signals when overexpressed although it does not contain typical death motifs such as the death domain, death effector domain, and caspase recruitment domain. Overexpression of FAF1 also decreases the basal level of NF-κ,B activity in transfected 293 cells, inhibits NF-κ,B activity induced by TNF-α, IL-1β, and lipopolysaccharide, and prevents NF-κ,B translocation to the nucleus, suggesting that another role of FAF1 is to negatively regulate the activity of NF-κ,B. FAF1 can also interact with the inflammatory signaling PYRIN-containing Apaf-1-like proteins (PYPAFs, also called NALPs) such as PYPAF1, PYPAF2 (NALP2), and PYPAF7, suggesting FAF1 may also be involved in the inflammation pathway. Multiple differentially spliced isoforms of FAF1 are known to exist.
- Poids moléculaire
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Predicted: 74 kDa
Observed: 80 kDa - ID gène
- 11124
- NCBI Accession
- NP_008982
- UniProt
- Q9UNN5
- Pathways
- Maintenance of Protein Location
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