BUB3 anticorps (C-Term)
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- Antigène Voir toutes BUB3 Anticorps
- BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BUB3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Purification
- Bub3 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- Bub3 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human bub3. The immunogen is located within the last 50 amino acids of Bub3.
- Isotype
- IgG
- Top Product
- Discover our top product BUB3 Anticorps primaire
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- Indications d'application
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Bub3 antibody can be used for detection of bub3 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Bub3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- Bub3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
- Autre désignation
- Bub3 (BUB3 Produits)
- Synonymes
- anticorps BUB3L, anticorps hBUB3, anticorps Aa2-050, anticorps xbub3, anticorps AU019800, anticorps AU021329, anticorps AU043350, anticorps AW146323, anticorps C78067, anticorps BUB3, mitotic checkpoint protein, anticorps BUB3 mitotic checkpoint protein, anticorps BUB3 mitotic checkpoint protein L homeolog, anticorps BUB3, anticorps Bub3, anticorps bub3.L
- Sujet
- Bub3 Antibody: The mitotic checkpoint protein Bub3 is involved with the essential spindle checkpoint pathway which operates during early embryogenesis. Bub3 is important during G2 and early mitosis stages, permitting entry into mitosis depending upon the assembly state of microtubules, thus preventing premature sister chromatid separation, mis-segregation and aneuploidy. Bub3 contains four WD repeat domains and is required for the kinetochore localization of Bub1, a related kinase that is necessary for spindle assembly checkpoint function. Bub1 is able to autophosphorylate and can catalyze the phosphorylation of Bub3. Both Bub1 and Bub3 are mutually dependent for function. Altered Bub expression levels may significantly impair mitotic checkpoint function and is associated with tumor cell proliferation.
- ID gène
- 9184
- UniProt
- O43684
- Pathways
- Maintenance of Protein Location
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